The test group experienced a significant reduction in wrinkles whereas placebo group showed no change.
*Double-blind, randomized, against placebo clinical study carried on 95 healthy men and woman subjects for 12 weeks.
Measured by (Ra, Rmax, Rp, Rz) Ra = Average roughness Rmax = Maximum Roughness Height Rp = Maximum Peak Height Rz = 10 point average roughness
Crow's Feet Wrinkles
The test group experienced a significant reduction in wrinkles whereas the placebo group showed no change.
*Double-blind, randomized, against placebo clinical study carried on 95 healthy men and woman subjects for 12 weeks.
Measured by (Ra, Rmax, Rp, Rz) Ra = Average roughness Rmax = Maximum Roughness Height Rp = Maximum Peak Height Rz = 10 point average roughness
Skin Hydration
The test group experienced 23% improvement in skin hydration whereas placebo group showed no change.
*Double-blind, randomized, against placebo. Carried on 40 healthy men and women subjects for 12 weeks.
Measured by (A.U) AU = Moisture Content
Skin Elasticity
The test group experienced 14% improvement in net skin elasticity whereas the placebo group showed no change.
*Double-blind, randomized, against placebo clinical study carried on 95 healthy men and woman subjects for 12 weeks.
Measured by (Ra, Rmax, Rp, Rz) Ra = Average roughness Rmax = Maximum Roughness Height Rp = Maximum Peak Height Rz = 10 point average roughness
Skin Firmness
The test group experienced 15% increase in skin firmness supported by 15% reduction in skin distensibility and 31% increase in skin echogenicity indicating higher density of collagen in the skin.
*Double-blind, randomized, against placebo clinical study carried on 95 healthy men and woman subjects for 12 weeks.
Measured by (Ra, Rmax, Rp, Rz) Ra = Average roughness Rmax = Maximum Roughness Height Rp = Maximum Peak Height Rz = 10 point average roughnessb
Skin Homogeneity
The test group experienced increased uniformity in skin tone, texture and appearance leading to brighter complexion and more even skin tone.
Measured using Visa Skin Analysis
Transepidermal Water Loss
18% lesser water vapour density was detected near the skin after 12 weeks. Indicating that lesser water has evaporated through the skin due to a stronger skin barrier.
02. IN VITRO STUDY
RSA 1.0 was shown to significantly increase collagen synthesis due to an increase of collagen synthase 3 (enzyme involved in collagen production).
And decrease in MMP13 Metallopeptidase 13 (enzyme involved in the breakdown of extracellular matrix containing collagen and tissue remodelling).
Human monocyte-derived macrophages (h-MDMs) and keratinocytes (HaCat) were co-cultivated in transwell culture system. The cells were stimulated with LPS (100ng/ml) to induce a pro-inflammatory phenotype and then were treated with RSA1.0 (1mg/ml). The expression of Collagen Synthase 3 (enzyme involved in collagen production), Metallopeptidase 13 (MMP13 involved in the breakdown of extracellular matrix containing collagen and tissue remodeling), TGF- and IL-10 (anti-inflammatory and proresolutive cytokines) were evaluated by real-time qPCR.
A single-arm study conducted with 70 healthy adults ages 25-40. We measured how participants reported feeling and behaving in different increments over the course of 2 months.
03. OBSERVATIONAL STUDY
With daily use over 2 months RSA 1.0 was seen to firm, brighten, minimise appearance of pores and reduce the appearance of wrinkles.
At 1 Month
100%
See a healthy glow in their skin
98%
Feel that their skin is firmer
94%
Feel that their skin is more hydrated, brighter and more radiant
At 2 Months
89%
Say that their pores look smaller
90%
See lighter pigmentation
95%
Say forehead and crows feet wrinkles appear smoother
One bottle. Daily. For healthier and younger looking skin.
